Experiment ID
165
Pathogen
Contains Preferred Model
0
Reference
Host type
# of Doses
3.00
Μodel
a
2.5E-01
N50
9.1E+07
LD50/ID50
9.1E+07
Dose Units
Response
Agent Strain
ETEC 214-4 (ST)
Exposure Route
Experiment Dataset
Description: 
Escherichia coli (ETEC 214-4 (ST)) in the human model data [1]
Dose Diarrhea or vomiting No diarrhea or vomiting Total
1E+06 0 4 4
1E+08 3 2 5
1E+10 4 1 5

 

Goodness of fit and model selection
Model Deviance Δ Degrees 
of freedom
χ20.95,1 
p-value
χ20.95,m-k 
p-value
Exponential 15.9 15.3 2 3.84 
9e-05
5.99 
0.000359
Beta Poisson 0.531 1 3.84 
0.466
Beta-Poisson fits better than exponential; cannot reject good fit for beta-Poisson.

 

Optimized parameters for the beta-Poisson model, from 10000 bootstrap iterations
Parameter MLE estimate Percentiles
0.5% 2.5% 5% 95% 97.5% 99.5%
α 2.5E-01 9.94E-04 9.94E-04 9.94E-04 1.76E+02 7.32E+02 7.32E+02
N50 9.1E+07 3.05E+04 4.09E+04 5.00E+04 3.20E+08 6.91E+08 6.91E+08

Parameter scatter plot for beta Poisson model ellipses signify the 0.9, 0.95 and 0.99 confidence of the parameters.

 

beta Poisson model plot, with confidence bounds around optimized model


References