Experiment ID
98
Pathogen
Contains Preferred Model
1
Reference
Host type
# of Doses
3.00
Μodel
a
1.55E-01
N50
2.11E+06
LD50/ID50
2.11E+06
Dose Units
Response
Agent Strain
EIEC 1624
Exposure Route
Experiment Dataset
Description: 
Escherichia coli (EIEC 1624) in the human model data[1]
Dose Positive stool isolation No positive stool isolation Total
1E+04 0 5 5
1E+06 5 4 9
1E+08 3 2 5

 

Goodness of fit and model selection
Model Deviance Δ Degrees 
of freedom
χ20.95,1 
p-value
χ20.95,m-k 
p-value
Exponential 28.6 27.2 2 3.84 
1.82e-07
5.99 
6.18e-07
Beta Poisson 1.38 1 3.84 
0.24
Beta-Poisson fits better than exponential; cannot reject good fit for beta-Poisson.

 

Optimized parameters for the beta-Poisson model, from 10000 bootstrap iterations
Parameter MLE estimate Percentiles
0.5% 2.5% 5% 95% 97.5% 99.5%
α 1.55E-01 1.26E-03 1.26E-03 2.84E-02 1.84E+01 1.29E+02 1.90E+02
N50 2.11E+06 1.73E+05 2.95E+05 2.95E+05 7.85E+08 9.22E+140 9.22E+140

Parameter scatter plot for beta Poisson model ellipses signify the 0.9, 0.95 and 0.99 confidence of the parameters.

beta Poisson model plot, with confidence bounds around optimized mode


References