Experiment ID
Acanth_Intranasal1
Agent Strain
A. culbertsoni (A1)
Contains Preferred Model
No
Exposure Route
intranasal
Response
death
Host type
mice
# of Doses
6.00
Dose Units
no of trophozoites
Μodel
beta-Poisson
a
0.161
N50
14,690 or 14,538
Experiment Dataset
Dose (no. of organisms) Positive Response Negative Response Total Subjects/Responses
3 0 20 20
30 2 18 20
300 1 19 20
3000 9 11 20
Description

Červa (1967a,b) studied white mice of the Czechoslovak H-strain weighing 13-15 grams inoculated intranasally by placing 0.02 mL of the A1 strain of Acanthamoeba over the nares of the ethyl-ether anesthetized mice (Cerva, 1967b).

The beta-Poisson model provided the best fit to the data. 

 

Cerva, L. (1967b). Intranasal, Intrapulmonary, and Intracardial Inoculation of Experimental Animals with Hartmanella castellanii. Folia Parasitologica (Praha), 14, 207–215.