Introduction
A total of 428 respiratory HAdV infections were studied from 1991 to 2007 in Korean children and the case fatality ratio was 5.1%
Hosts
Animals and humans [1]
Transmission / Exposure Route
Direct contact, fecal-oral transmission, and occasionally waterborne transmission [1]
Case Fatality Ratio
Case Fatality Ratio | Pathway/conditions | Population | References |
48%(of over 300) | Immunocompromised | [2] | |
5.1%(of 428) | 1991-2007 Korean Children | [3] |
Incubation Period
3-10 days
Burden of Disease
Adenoviruses C in non-hospitalized Mexican children older than five years of age showed a rate of AdV infection of 23%. [4]
Duration of infectiousness and disease
Symptomology
Symptoms include colds, sore throat, bronchitis, pneumonia, diarrhea, pink eye, fever, bladder inflammation or infection, inflammation of stomach and and intestines, and neurologic disease. These symptoms can vary depending on how a person becomes infected. For example, breathing in adenovirus may be more likely to cause respiratory illnesses. [5]
Excretion Rates (see Exposure)
Adenovirus can persist in the tonsils, adenoids, and intestines for months or years. This is a persistent adenovirus infection which usually shows no symptoms. [5]
Immunity
Currently there is no vaccine available to the general public. However, military personnel can obtain a vaccine for adenovirus types 4 and 7. [5]
Microbiology
Medium-sized (90-100 nm), nonenveloped icosohedral viruses containing double-stranded DNA [5]
Enviromental Survival
Unusually stable to chemical and physical agents and to adverse pH conditions [1]