Introduction
Prion-related diseases are relentlessly progressive and invariably lead to death (Medscape)
Hosts
Human and animal [1]
Transmission / Exposure Route
Primary method of infection in animals is through ingestion[2]
Case Fatality Ratio
Prion-related diseases are relentlessly progressive and invariably lead to death. [2]
Incubation Period
Incubation periods of infection with human prions can exceed 50 years[3]
Burden of Disease
The most common prion disease is CJD, with a uniform incidence of approximately 1 case per million population both in the United States and internationally[2]
Duration of Infectiousness and disease
Symptomology
Latency
Asymptomatic Rates
Excretion Rates (see Exposure)
Immunity
Microbiology
An infectious agent composed of protein in a misfolded form
