| ID | Exposure Route | # of Doses | Agent Strain | Dose Units | Host type | Μodel | LD50/ID50 | Optimized parameters | Response type | Reference |
|---|---|---|---|---|---|---|---|---|---|---|
| 289 | intubation | 8.00 | CFU | rhesus monkey | beta-Poisson | 8.26E+08 | a = 0.04 N50 = 8.26E+08 | stillbirths | ||
| 290 | intubation | 5.00 | CFU | guinea pig | beta-Poisson | 4.67E+07 | a = 0.0936 N50 = 4.67E+07 | fetal mortality | ||
| 292 | oral | 6.00 | F5817 | CFU | beta-Poisson | a = 0.253 N50 = 277 | infection |
Exposure Route:
intubation
# of Doses:
8.00
Agent Strain:
Dose Units:
CFU
Host type:
rhesus monkey
Μodel:
beta-Poisson
LD50/ID50:
8.26E+08
Optimized parameters:
a = 0.04
N50 = 8.26E+08
Response type:
stillbirths
Reference:
Exposure Route:
intubation
# of Doses:
5.00
Agent Strain:
Dose Units:
CFU
Host type:
guinea pig
Μodel:
beta-Poisson
LD50/ID50:
4.67E+07
Optimized parameters:
a = 0.0936
N50 = 4.67E+07
Response type:
fetal mortality
Reference:
Exposure Route:
oral
# of Doses:
6.00
Agent Strain:
F5817
Dose Units:
CFU
Host type:
Μodel:
beta-Poisson
LD50/ID50:
Optimized parameters:
a = 0.253
N50 = 277
Response type:
infection
Reference:
| Model | Deviance | Δ | Degrees of freedom |
χ20.95,1 p-value |
χ20.95,m-k p-value |
| Exponential | 9.88 | 6.48 | 5 | 3.84 0.011 |
11.1 0.0788 |
| beta Poisson | 3.4 | 4 | 9.49 0.494 |
||
| beta-Poisson fits better than exponential; can not reject good fit for beta-Poisson | |||||
| Parameter | MLE Estimate | 0.5% | 2.5% | 5% | 95% | 97.5% | 99.5% |
| α | 6.95E-01 | 2.69E-01 | 3.39E-01 | 3.78E-01 | 2.56E+0 | 2.28E+01 | 1.18E+03 |
| N50 | 3.39E+03 | 3.58E+01 | 2.47E+02 | 4.67E+02 | 1.09E+04 | 1.26E+04 | 1.85E+04 |