Host type
# of Doses
8.00
Μodel
a
2.53E-0.2
N50
6.17E+00
LD50/ID50
6.17E+00
Dose Units
Exposure Route
Experiment Dataset
Description: 
Model data for rotavirus (CJN strain) in the human [1]
Dose Infected Non-infected Total
9E-03 0 7 7
0.09 0 7 7
0.9 1 6 7
9 8 3 11
90 6 1 7
900 7 1 8
9000 5 2 7
9E+04 3 0 3

 

Goodness of fit and model selection
Model Deviance Δ Degrees 
of freedom
χ20.95,1 
p-value
χ20.95,m-k 
p-value
Exponential 125 119 7 3.84 
0
14.1 
0
Beta Poisson 6.2 6 12.6 
0.401
Beta-Poisson fits better than exponential; cannot reject good fit for beta-Poisson.

 

Optimized parameters for the beta-Poisson model, from 10000 bootstrap iterations
Parameter MLE estimate Percentiles
0.5% 2.5% 5% 95% 97.5% 99.5%
α 2.53E-01 1.28E-01 1.51E-01 1.64E-01 5.18E-01 6.58E-01 6.76E+02
N50 6.17E+00 1.46E+00 2.17E+00 2.49E+00 1.89E+01 2.49E+01 4.37E+01

 

Parameter scatter plot for beta Poisson model ellipses signify the 0.9, 0.95 and 0.99 confidence of the parameters

beta Poisson model plot, with confidence bounds around optimized model


References