Experiment ID
80
Pathogen
Contains Preferred Model
0
Reference
Host type
# of Doses
5.00
Μodel
a
2.03E-01
N50
8.53E+05
LD50/ID50
8.53E+05
Dose Units
Response
Agent Strain
Quailes
Exposure Route
Experiment Dataset
Description: 
Model data for S. Typhi (Quailes) in humans [4]
Dose Disease No disease Total
1000 0 14 14
1E+05 32 84 116
1E+07 16 16 32
1E+08 8 1 9
1E+09 40 2 42

 

Goodness of fit and model selection
Model Deviance Δ Degrees 
of freedom
χ20.95,1 
p-value
χ20.95,m-k 
p-value
Exponential 293 284 4 3.84 
0
9.49 
0
Beta Poisson 8.63 3 7.81 
0.0346
Neither the exponential nor beta-Poisson fits well; beta-Poisson is less bad.

 

Optimized parameters for the beta-Poisson model, from 10000 bootstrap iterations
Parameter MLE estimate Percentiles
0.5% 2.5% 5% 95% 97.5% 99.5%
α 2.03E-01 1.33E-01 1.49E-01 1.57E-01 2.74E-01 2.89E-01 3.27E-01
N50 8.53E+05 3.38E+05 4.28E+05 4.80E+05 1.62E+06 1.85E+06 2.49E+06

 

Parameter scatter plot for beta Poisson model ellipses signify the 0.9, 0.95 and 0.99 confidence of the parameters.

beta Poisson model plot, with confidence bounds around optimized model