Optimization Output for Exp. 184

Basic Information

Experiment ID	184
Pathogen	Campylobacter jejuni
Contains Preferred Model	0
Reference	Experimental Campylobacter jejuni Infection of Adult Mice

Detailed information

Host type

# of Doses

5.00

Μodel

9.01E-07

LD50/ID50

7.69E+05

Dose Units

Response

Agent Strain

type strain for serotype PEN 1

Exposure Route

Experiment Dataset

Description:

**Goodness of fit and model selection**
Model	Deviance	Δ	Degrees of freedom	χ²_0.95,1 p-value	χ²_0.95,m-k p-value
Exponential	0.0918	-0.000599	4	3.84 1	9.49 0.999
Beta Poisson	0.0924	-0.000599	3	3.84 1	7.81 0.993
Exponential is preferred to beta-Poisson; cannot reject good fit for exponential.

**Optimized k parameter for the exponential model, from 10000 bootstrap iterations**
Parameter	MLE estimate	Percentiles
Parameter	MLE estimate	0.5%	2.5%	5%	95%	97.5%	99.5%
k	9.01E-07	4.61E-08	2.21E-07	2.21E-07	4.61E-06	4.61E-06	4.61E-06
ID50/LD50/ETC*	7.69E+05	1.51E+05	1.51E+05	1.51E+05	3.14E+06	3.14E+06	1.51E+07
*Not a parameter of the exponential model; however, it facilitates comparison with other models.

Parameter histogram for exponential model (uncertainty of the parameter)

Exponential model plot, with confidence bounds around optimized model

References