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Introduction

Less than 1% for people aged 24 or younger, 6% for those 25 to 44, 15% for those 45 to 64, and more than 50% for those over 65 (Update 49)

Hosts

Humans

Transmission / Exposure Route

Primarily via close person-to-person contact, through droplet transmission [1]

Case Fatality Ratio

Less than 1% for people aged 24 or younger, 6% for those 25 to 44, 15% for those 45 to 64, and more than 50% for those over 65[2]

Case Fatality Ratios
Age (Years) Case Fatality Ratio
< 24 < 1%
25-44 6%
45-64 15%
> 65 > 50%

Incubation Period

Maximum is 10 days [2]

Burden of Disease

In the 2002-2003 outbreak, more than 8,000 cases were identified, mostly in mainland China. North America saw 251 cases during that period [3]

Duration of Infectiousness and disease

Symptomology

A high fever is typical (upwards of 38°C) at onset, after which headaches, general malaise, and diarrhea can occur. After 2 to 7 days, a dry cough may develop. Pneumonia is typical of most SARS patients.[4]

Latency

Asymptomatic Rates

Excretion Rates (see Exposure)

Immunity

Microbiology

Coronaviruses are positive-strand, enveloped RNA viruses [5]

Dose Response Models

Route: intranasal, Response: death

exponential

\[P(response)=1-exp(-k\times dose)\]

Optimized parameters:
k = 2.46E-03
LD50 = 2.82E+02

Data from Other Sources

Read more:

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by {{author}} On Global Water Pathogen Project

Classification:

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Other names:

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NCBI Publications on Risk Assesment:

The NCBI Web Service is currently unavailable.