Ojielo et al. (2003)

Basic Information

Experiment ID	Ojielo2003
Pathogen	Pseudomonas aeruginosa
Contains Preferred Model	0
Status	fitted
Reference	Defective Phagocytosis and Clearance of <i>Pseudomonas aeruginosa</i> in the Lung Following Bone Marrow Transplantation

Detailed information

Host type

# of Doses

7.00

Μodel

3.22E-7

Dose Units

Response

Agent Strain

PA01

Exposure Route

Experiment Dataset

Description:

**Table 1: Goodness of fit**
Model	Deviance	Δ	Degrees of freedom	χ²_0.95,1 p-value	χ²_0.95,m-k p-value
Exponential	16.88	0.001	6	3.84 0.98	12.6 0.009
Beta Poisson	16.88	0.001	5	3.84 0.98	11.1 0.004
Neither model provides a good fit to the data

**Table 2: Multi-hit dose response statistics**
Model	Deviance	Δ	DF	χ²_0.95,df	χ²_0.95,1	Good fit?	Parameters	LD50
Multi-hit	1.09	15.69	5	11.1	3.84	Yes	k = 4.12 × 10⁻⁶ k_min=11	2,588,047

Fig. 1. The multi-hit dose response model with 95% and 99% confidence bands

Fig 2. Histogram of the k parameter estimates after bootstrapping

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