Experiment ID
63
Pathogen
Contains Preferred Model
1
Reference
Host type
# of Doses
3.00
Μodel
k
3.74E-03
LD50/ID50
1.85E+02
Dose Units
Response
Agent Strain
porcine, PE7-05i
Exposure Route
Experiment Dataset
Description: 
pigs/ Porcine enterovirus type 7 [1]
Dose infected Non-infected Total
250 4 2 6
250 3 3 6
1000 5 0 5

 

Goodness of fit and model selection
Model Deviance Δ Degrees 
of freedom
χ20.95,1 
p-value
χ20.95,m-k 
p-value
Exponential 0.614 -5.49e-05 2 3.84 
1
5.99 
0.736
Beta Poisson 0.614 1 3.84 
0.433
Exponential is preferred to beta-Poisson; cannot reject good fit for exponential.

 

Optimized k parameter for the exponential model, from 10000 bootstrap iterations
Parameter MLE estimate Percentiles
0.5% 2.5% 5% 95% 97.5% 99.5%
k 3.74E-03 1.83E-03 2.19E-03 2.19E-03 5.62E-03 5.62E-03 5.62E-03
ID50/LD50/ETC* 1.85E+02 1.23E+02 1.23E+02 1.23E+02 3.16E+02 3.16E+02 3.79E+02
*Not a parameter of the exponential model; however, it facilitates comparison with other models.

 

Parameter histogram for exponential model (uncertainty of the parameter)

Exponential model plot, with confidence bounds around optimized model


References

  1. Cliver, D. O. (1981).  Experimental infection by waterborne enteroviruses. Journal of Food Protection. 44, 861-865.