Table of contents

Introduction

Hand, Foot, and Mouth Disease caused by enterovirus in China between 2008 and 2009 was studied and the case fatality ratio was 0.03% (Zhang et al, 2011)

Hosts

Human and animal

Transmission / Exposure Route

Fecal-oral, indirectly through contact with dirty hands or objects

Case Fatality Ratio

Case fatality ratios
Case Fatality Ratio Pathway/conditions Population References
0.03%   Chinese (2008-2009) [1]
5-7%   Pre-vaccine era [2]

Incubation Period

3-10 days [2]

Burden of Disease

Hand, Foot, and Mouth Disease caused by enterovirus in China between 2008 and 2009 was studied and the incidence rate was 57.9%[1]

Duration of infectiousness and disease

Symptomology

Latency

Asymptomatic Rates

Excretion Rates (see Exposure)

Immunity

Microbiology

Member of the picornavirus family, a large and diverse group of small RNA viruses characterized by a single positive-strand genomic RNA, icosahedral nonenveloped viruses that are approximately 30 nm in diameter[3]

Enviromental Survival

Enteroviruses resist lipid solvents, ether, chloroform, and alcohol. They are inactivated at temperatures above 50°C but remain infectious at refrigerator temperature.[2]

exponential

\[P(response)=1-exp(-k\times dose)\]

Optimized parameters:
k = 3.74E-03
ID50 = 1.85E+02

Data from other sources:


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