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The overall mortality rate for E. coli O157:H7 is <1%. For those who develop hemolytic uremic syndrome, the death rate is between 3-5% (www.azdhs.gov)


Animals and humans

Transmission / Exposure Route

Fecal-oral route, and most illness has been associated with eating undercooked, contaminated ground beef, swimming in or drinking contaminated water, and eating contaminated vegetables; but direct person-to-person contact can also spread infection[1]

Case Fatality Ratio

Case fatality ratios
Case Fatality Ratio Pathway/conditions Population References
8% Neonatal Meningitis Not Reported [2]
3-5% Developed hemolytic uremic syndrome Not Reported [1]
<1% Not Reported Overall [1]

Incubation Period

The incubation time for E. coli O157:H7 can be from 2 to 8 days, but it usually ranges from 3 to 4 days[1]

Burden of Disease

The incidence of E. coli O157:H7 and non-O157 infection per 100,000 population in 2008 is 1.12 and 0.45.[3]

Duration of infectiousness and disease


Severe stomach cramps, diarrhea, and vomiting are common symptoms of E. coli O157:H7 infections. Fever can occur but is usually less than 38.5˚C. Symptoms generally subside within 5-7 days, although more extreme cases do exist. [4]

Excretion Rates (see Exposure)



Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms.[5]


Dose Response Models

Route: oral (in milk), Response: positive stool isolation


$$P(response)=1-[1+dose\frac{2^{\frac{1}{a}}-1}{N^{50}} ]^{-a}$$

Optimized parameters:
a = 1.55E-01
N50 = 2.11E+06
ID50 = 2.11E+06

Data from Other Sources

Read more:


by {{author}} On Global Water Pathogen Project


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Other names:

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NCBI Publications on Risk Assesment:

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