Prion

Introduction

Prion-related diseases are relentlessly progressive and invariably lead to death (Medscape)

Hosts

Human and animal ^[1]

Transmission / Exposure Route

Primary method of infection in animals is through ingestion^[2]

Case Fatality Ratio

Prion-related diseases are relentlessly progressive and invariably lead to death. ^[2]

Incubation Period

Incubation periods of infection with human prions can exceed 50 years^[3]

Burden of Disease

The most common prion disease is CJD, with a uniform incidence of approximately 1 case per million population both in the United States and internationally^[2]

Duration of Infectiousness and disease

Symptomology

Latency

Asymptomatic Rates

Excretion Rates (see Exposure)

Immunity

Microbiology

An infectious agent composed of protein in a misfolded form