Description
Table 1: Goodness of fit
Model Deviance Δ Degrees 
of freedom		 χ20.95,1 
p-value 		χ20.95,m-k 
p-value
Exponential 16.88 0.001 6 3.84 
0.98 		12.6
0.009
Beta Poisson 16.88 5 11.1
0.004
Neither model provides a good fit to the data

 

Table 2: Multi-hit dose response statistics
Model Deviance Δ DF χ20.95,df χ20.95,1 Good fit? Parameters LD50
Multi-hit 1.09 15.69 5 11.1 3.84 Yes k = 4.12 × 10−6 kmin=11 2,588,047

 

Figure 1. The multi-hit dose response model with 95% and 99% confidence bands
Figure 1. The multi-hit dose response model with 95% and 99% confidence bands

 

 

Figure 2. Histogram of the k parameter estimates after bootstrapping
Figure 2. Histogram of the k parameter estimates after bootstrapping

 

# of Doses
7.00
Μodel
exponential
Dose Units
CFU
Response
death
Exposure Route
intratracheal
Contains Preferred Model
Status
fitted
k
3.22E-7
Agent Strain
PA01
Experiment ID
Ojielo2003
Host type
C57BL/6 mice
Experiment Dataset
Dose (CFU) Positive Response Negative Response
80000 0 10
400000 0 10
900000 0 10
2000000 2 5
3000000 6 4
4500000 10 0
8000000 10 0
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