Description
BALB/c Mice KHW Strain Data 
Dose Infected Non-infected Total
5 0 6 6
15 0 6 6
45 3 1 4
135 4 2 6
405 6 0 6

 

Goodness of fit and model selection
Model Deviance Δ Degrees 
of freedom		 χ20.95,1 
p-value 		χ20.95,m-k 
p-value
Exponential 5.25 -0.000362 4 3.84 
1 		9.49 
0.263
Beta Poisson 5.25 3 7.81 
0.154
Exponential is preferred to beta-Poisson; cannot reject good fit for exponential.

 

Optimized parameters for the exponential model, from 10000 bootstrap iterations
Parameter MLE estimate Percentiles
0.5% 2.5% 5% 95% 97.5% 99.5%
k 1.04E-02 4.94E-03 5.96E-03 6.60E-03 1.92E-02 2.45E-02 2.45E-02
ID50/LD50/ETC* 6.63E+01 2.82E+01 2.82E+01 3.61E+01 1.05E+02 1.16E+02 1.40E+02
*Not a parameter of the exponential model; however, it facilitates comparison with other models.
Parameter histogram for exponential model (uncertainty of the parameter)
Parameter histogram for exponential model (uncertainty of the parameter)

 

Exponential model plot, with confidence bounds around optimized model
Exponential model plot, with confidence bounds around optimized model

 

 

 

# of Doses
5.00
Μodel
exponential
LD50/ID50
6.63E+01
Dose Units
CFU
Response
infection
Exposure Route
intranasal
Contains Preferred Model
k
1.04E-02
Agent Strain
KHW
Experiment ID
17
Host type
BALB/c mice
Experiment Dataset
Subscribe to BALB/c mice