Badenoch et al. (1990) studied the combined effect of Acanthamoeba Ac118 (a group III isolate) and the bacterium Corynebacterium xerosis on the corneas of female Portion rats. A constant dose of 106 C. xerosis with increasing doses of Acanthamoeba spp. were injected into incisions in the rat corneas using a microsyringe.
The exponential model provided the best fit to the data.
Dose (no. of organisms) | Positive Response | Negative Response | Total Subjects/Responses | |
---|---|---|---|---|
10 | 0 | 8 | 8 | |
100 | 0 | 16 | 16 | |
1000 | 7 | 17 | 24 | |
10000 | 10 | 0 | 10 |
Badenoch et al. (1990) studied the combined effect of Acanthamoeba Ac118 (a group III isolate) and the bacterium Corynebacterium xerosis on the corneas of female Porton rats. A constant dose of 104 C. xerosis with increasing doses of Acanthamoeba spp. were injected into incisions in the rat corneas using a microsyringe (Badenoch et al. 1990).
The exponential model provided the best fit to the data.
Dose (no. of organisms) | Positive Responses | Negative Responses | Total Subjects/Responses | |
---|---|---|---|---|
10 | 0 | 8 | 8 | |
100 | 0 | 16 | 16 | |
1000 | 2 | 16 | 18 | |
10000 | 5 | 3 | 8 |